N-[4-(aMinosuIfonyI)phenyI]acrylaMide
N-[4-(aminosulphonyl)phenyl]acrylamide
CAS: 2621-99-0
Molecular Formula: C9H10N2O3S
N-[4-(aMinosuIfonyI)phenyI]acrylaMide - Names and Identifiers
N-[4-(aMinosuIfonyI)phenyI]acrylaMide - Physico-chemical Properties
| Molecular Formula | C9H10N2O3S |
| Molar Mass | 226.25 |
| Density | 1.387±0.06 g/cm3(Predicted) |
| Melting Point | 215 °C |
| pKa | 9.89±0.12(Predicted) |
| Use | Overview N-[4-(sulfonamide) phenyl] Acrylamide (ASPAA) monomer can be homopolymerized or copolymerized with other monomers to synthesize a polymer with pharmacological activity, which is water-soluble and has little toxic and side effects, macromolecular drugs with sustained-release effect. At the same time, due to the certain alkali solubility of the sulfonamide group, the copolymer of ASPAA and acrylic ester and other monomers can be used to prepare the lithographic printing with good properties such as alkali developing, developing latitude and printing resistance, computer direct plate. |
N-[4-(aMinosuIfonyI)phenyI]acrylaMide - Reference Information
| overview | N-[4-(sulfonamide) phenyl] acrylamide (ASPAA) monomers can be homopolymerized or copolymerized with other monomers to synthesize polymers with pharmacological activities, and make macromolecular drugs with water solubility, low toxic and side effects, and slow-release effects. At the same time, because the sulfonamide group has a certain alkali solubility, the copolymer of ASPAA and acrylates and other monomers can be used to prepare flat printing and computer direct plate-making plates with good properties such as alkali development, development tolerance and printing resistance. |
| Preparation | Sulfanilamide (1.00g) and pyridine (1.41mL) were added to 1, 4-dioxane (30mL). Acrylyl chloride (0.49mL) was added drop by drop, and the solution was stirred at room temperature for 3 hours. 1M HCl was added and the solution was extracted with ethyl acetate. The extract is dried with salt water and anhydrous sodium sulfate to remove the solvent to obtain a crude product of sufficient purity for subsequent use. |
Last Update：2024-04-10 22:29:15
N-[4-(aMinosuIfonyI)phenyI]acrylaMide - Nature
| melting point | 215 °C |
| density | 1.387±0.06 g/cm3(Predicted) |
| acidity coefficient (pKa) | 9.89±0.12(Predicted) |
Last Update：2024-04-09 20:52:54
N-[4-(aMinosuIfonyI)phenyI]acrylaMide - Uses and synthesis methods
| overview | N-[4-(sulfonamide) phenyl] acrylamide (ASPAA) monomers can be homopolymerized or copolymerized with other monomers to synthesize polymers with pharmacological activity, and are made into macromolecular drugs with water solubility, little toxic and side effects, and slow release effect. At the same time, because the sulfonamide group has a certain alkali solubility, the copolymer of ASPAA and acrylates and other monomers can be used to prepare flat printing and computer direct plate-making plates with good properties such as alkali development, development tolerance and printing resistance. |
| preparation |
Sulfanilamide (1.00g) and pyridine (1.41mL) were added to 1, 4-dioxane (30mL). Acrylyl chloride (0.49mL) was added drop by drop, and the solution was stirred at room temperature for 3 hours. 1M HCl was added and the solution was extracted with ethyl acetate. The extract is dried with brine and anhydrous sodium sulfate to remove the solvent to obtain a crude product of sufficient purity for subsequent use. |
Last Update：2024-04-09 22:09:11
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